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Cleocin-T Gel

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Drug Uses

Cleocin T is used to treat acne vulgaris.

How Taken

Apply a thin film of Cleocin T Topical Solution or use a Cleocin T Topical Solution pledget for the application of Cleocin T twice daily to affected area. You may use more than one pledget. Use each pledget only once and then discard it.

Warnings/Precautions

It is not known whether clindamycin is excreted in human milk following use of Cleocin T. However, orally and parenterally administered clindamycin has been reported to appear in breast milk.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Possible Side Effects

Orally and parenterally administered Cleocin T has been associated with severe colitis which may end fatally. Abdominal pain and gastrointestinal disturbances as well as gram-negative folliculitis have also been reported in association with the use of topical formulations of clindamycin.

Storage

Do not use pledget if the seal is broken. Discard after single use. Keep all liquid dosage forms in containers tightly closed out of the reach of children.

Overdose

Topically applied Cleocin T can be absorbed in sufficient amounts to produce systemic effects. Seek emergency medical attention if an overdose is suspected.

More Information

Use caution when taking Cleocin T together with neuromuscular blocking agents.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

Other info about Cleocin-t-gel at Wikipedia.org and other resources:


Highly sensitive determination of hydroxylamine using fused gold nanoparticles immobilized on sol-gel film modified gold electrode.
Authors: Kannan P, John SA We are reporting the highly sensitive determination of hydroxylamine (HA) using 2-mercapto-4-methyl-5-thiazoleacetic acid (TAA) capped fused spherical gold nanoparticles (AuNPs) modified Au electrode. The fused TAA-AuNPs were immobilized on (3-mercaptopropyl)-trimethoxysilane (MPTS) sol-gel film, which was pre-assembled on Au electrode. The immobilization of fused TAA-AuNPs on MPTS sol-gel film was confirmed by UV-vis absorption spectroscopy and atomic force microscopy (AFM). The AFM image showed that the AuNPs retained the fused spherical morphology after immobilized on sol-gel film. The fused TAA-AuNPs on MPTS modified Au electrode were used for the determination of HA in phosphate buffer (PB) solution (pH=7.2). When compared to bare Au electrode, the fused...

Ingenol Mebutate Gel Clears Actinic Keratosis Lesions
An investigational plant extract gel, ingenol mebutate 0.05%, is well tolerated and highly effective in clearing actinic keratosis lesions. Medscape Medical News (Source: Medscape Today Headlines)

Nasal mucoadhesive
The objective of this study was to develop an intranasal delivery system of ondansetron hydrochloride using thermo-sensitive polymer PF127 and mucoadhesive polymer hydroxypropylcellulose. Due to increase in bioadhesive polymer concentration, there was increase in bioadhesion strength, at the same time there was decrease in the spredability. An in vitro diffusion study revealed that viscosity of the vehicle has an influence on drug. The release of ondansetron hydrochloride from the gel matrix showed diffusion- controlled. (Source: Indian Journal of Pharmaceutical Sciences)

Novel nasal
Mehta M R, Surve S A, Menon M DIndian Journal of Pharmaceutical Sciences 2009 71(6):721-722In situ gelling systems based on temperature-dependent phase transition containing pheniramine and phenylephrine were developed using combination of Poloxamers, different cellulose polymers (HPMC) and xanthan gum. The formulations were tested for in vitro gelation, appearance, pH, drug content, in vitro drug release, mucoadhesive strength, preservative efficacy and stability. In vitro release studies revealed significant prolonged released of both drugs up to 24 h as against only 2 h with drug solution. Formulations were found to stable over period of 3 months. In vivo nasal residence time of in situ gel by gamma scintigraphy was found to be significantly higher (6 h) in comparison to drug solution (...

Delta2D and Proteomweaver: Performance evaluation of two different approaches for 2-DE analysis
2-DE is a fundamental technology used in proteomics research. However, despite its high capacity to simultaneously separate several proteins for subsequent identification and quantitative comparison studies, a drawback for this technique is its limited reproducibility, especially when comparing data from different laboratories. 2-DE-related variability can be broadly divided into two categories: experimental and post-experimental. Experimental variability depends on physical and chemical parameters, whereas post-experimental variability arises when gels are analyzed by different software packages, particularly when different workflows are followed. In this paper, we compared the analysis performance of two software packages, Delta2D and Proteomweaver, using both standard and experimental g...


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