Drug Uses

Norvasc is in a class of drugs called calcium channel blockers. Norvasc relaxes (widens) the blood vessels (veins and arteries), making it easier for the heart to pump and reducing its workload. Norvasc is used to treat hypertension (high blood pressure) and to treat angina (chest pain). Norvasc may also be used for purposes other than those listed in this medication guide.

How Taken

Norvasc comes as a tablet to take it orally. It is usually taken once a day. Norvasc may cause an upset stomach. Take Norvasc with food or milk. Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

Warnings/Precautions

Before taking Norvasc, tell your doctor if you have liver disease; or another disease of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease. You may not be able to take Norvasc, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Norvasc is in the FDA pregnancy category C. This means that it is not known whether Norvasc will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Norvasc passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

Possible Side Effects

If you experience any of the following serious side effects, stop taking Norvasc and contact your doctor immediately or seek emergency medical treatment:
-an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives
-unusually fast or slow heartbeat;
-chest pain;
-severe dizziness or fainting;
-psychosis;
-jaundice (yellowing of the skin or eyes); or
-swelling of the legs or ankles.
Other, less serious side effects may be more likely to occur. Continue to take Norvasc and talk to your doctor if you experience
-fatigue or tiredness;
-headache;
-insomnia;
-vivid or abnormal dreams;
-flushing;
-abdominal pain;
-nausea, diarrhea, or constipation; or
-increased or difficult urination.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Store bottles at controlled room temperature, 59° to 86°F (15° to 30°C) and dispense in tight, light-resistant containers.

Overdose

Over dosage might be expected to cause excessive peripheral vasodilatation with marked hypotension and possibly a reflex tachycardia. Symptoms of Norvasc overdose include dizziness, weakness, and chest pain, shortness of breath, fainting, unusually fast or slow heartbeat, coma, slurred speech, and confusion.

More Information

Before taking Norvasc, tell your doctor if you have liver disease or another disease of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease. If you are over 65 years of age, you may be more likely to experience side effects from Norvasc. Your doctor may prescribe a lower dose of this medication.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

Other info about Norvasc at Wikipedia.org and other resources:

NORVASC (Amlodipine Besylate) Tablet [Pfizer Laboratories Div Pfizer Inc]
Updated Date: Feb 25, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Antihypertensive Combo May Save Kidney Function (CME/CE)
Patients with chronic kidney disease treated with benazepril (Lotensin) plus amlodipine (Norvasc) were less likely to experience worsening renal function than those treated with benazepril plus hydrochlorothiazide, researchers found. (Source: MedPage Today Cardiovascular)

Report: Combo hypertension drugs could provide lower doses, be safer
A fixed-dose combination of two hypertension drugs, like telmisartan (Micardis, Boehringer Ingelheim) and amlodipine (Norvasc, Pfizer) that have a lower dosage than valsartan (Diovan/Tareg, Novartis), would have an estimated gain in patient shares, according to a survey of U.S. and European cardiologists conducted by marketing research firm Decision Resources. (Source: Cardiovascular Business News)

The epidemiology of Takayasu arteritis in the UK
Conclusion. This is the first population-based study of the epidemiology of TAK. The annual incidence and prevalence are consistent with previous studies. (Source: Rheumatology)

Pfizer To Appeal Canadian Federal Court Decision On Company's Norvasc Patent
NEW YORK--(BUSINESS WIRE)--Jul 9, 2009 - Pfizer Inc said today that it is disappointed by the Canadian Federal Court's decision declaring invalid its patent covering amlodipine besylate, the active ingredient in Norvasc®, and that the company... (Source: Drugs.com - Pharma News)