Drug Uses

Use Tetracycline to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

How Taken

The usual daily dose is 1g to 2g. Your doctor may increase the dosage in case of severe infections. You should continue therapy for at least 24 to 48 hours after the symptoms and fever have subsided.

Warnings/Precautions

Talk to your physician before taking this medicine if you are hypersensitive to tetracyclines. Using Tetracycline in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit and increases the risk of the development of drug-resistant bacteria.

Missed Dose

If you skip doses or do not complete the full course of therapy, you may risk a decrease in the effectiveness of the immediate treatment. Also there is a chance that bacteria will develop resistance and will not be treatable by Tetracycline or other antibacterial drugs in the future.

Possible Side Effects

Side effects you may experience may include: anorexia, epigastric distress, nausea, vomiting, diarrhea, bulky loose stools, stomatitis, sore throat, glossitis, black hairy tongue, dysphagia, hoarseness, enterocolitis, and inflammatory lesions (with candidal overgrowth) in the anogenital region.

Storage

Store the tablets at room temperature; avoid excessive heat. Dispense in tight, light-resistant containers. Keep out of the reach of children.

Overdose

In case of overdosage, seek emergency medical attention.

More Information

If you are undergoing long-term therapy, periodic laboratory evaluation of organ system function, including renal, hepatic, and hematopoietic systems, should be performed.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

Other info about Tetracycline at Wikipedia.org and other resources:

Antibiotic susceptibility profiles and first report of TEM extended-spectrum β-lactamase in Pseudomonas fluorescens from coastal waters of the Kaštela Bay, Croatia
Abstract  The aim of this study was to investigate the antibiotic susceptibility profiles and the presence of extended-spectrum-β-lactamases (ESBLs) in Pseudomonas fluorescens isolates from coastal waters of the Kaštela Bay, Croatia. Twenty-two water samples were collected during 2009. Isolates were tested for susceptibilities to 13 antibiotics by Etest. ESBL production was confirmed by double-disk synergy test carried out on Mueller–Hinton agar plates containing efflux pump inhibitor Phe-Arg-β-naphthylamide dihydrochloride. PCR and DNA sequencing analysis were used to identify ESBL-encoding genes. The transferability of cephalosporin resistance was tested by conjugation experiments. Genetic relatedness of ESBL-producing isolates was determined by random amplified polym...

A Hoxb13‐driven reverse tetracycline transactivator system for conditional gene expression in the prostate
CONCLUSIONSThe Hoxb13‐rtTA transgenic system provides a powerful tool for conditional Tet operator‐driven transgene expression in the normal prostate and during disease progression. Used in conjunction with other prostate pathology models, these mice will enable precise, temporally controlled analyses of gene function and can provide opportunities for detailed analyses of molecular events underlying prostate diseases. Prostate © 2012 Wiley Periodicals, Inc. (Source: The Prostate)

Doxycycline ameliorates the dystrophic phenotype of skeletal and cardiac muscles in mdx mice.
This study provides evidence that doxycycline may be a potential therapeutic agent for DMD. (Source: Muscle and Nerve)

Genetic analysis of multiple antimicrobial resistance in Salmonella isolated from diseased broilers in Egypt
ABSTRACTTo date, no information is available on the molecular bases of antimicrobial resistance in Salmonella spp. from poultry in Egypt or even in Africa. Therefore, the objective of this study was to analyze, at the molecular level, the mechanism of multidrug‐resistance in isolates of Salmonella recovered from diseased broilers in Egypt. A total of 21 Salmonella isolates were identified; 13 isolates were Salmonella enterica serovar Enteritidis and eight isolates were Salmonella enterica serovar Typhimurium. 17 (81%) Salmonella isolates displayed multidrug resistance phenotypes, particularly against ampicillin, streptomycin, spectinomycin, kanamycin, tetracycline, chloramphenicol, and trimethoprim/sulfamethoxazole. PCR and DNA sequencing identified class 1 integrons in nine (42.9%) isol...

Cotrimoxazole Prophylaxis Specifically Selects for Cotrimoxazole Resistance in Streptococcus mutans and Streptococcus sobrinus with Varied Polymorphisms in the Target Genes folA and folP
The selection of antibiotic resistance by cotrimoxazole prophylaxis was evaluated, and we characterized the mechanism of cotrimoxazole resistance in Streptococcus mutans and Streptococcus sobrinus. In vitro susceptibility to six antibiotics was evaluated on 64 mutans streptococci group (MSG) isolates from a cotrimoxazole prophylaxis group and compared to 84 MSG isolates from a nonprophylaxis group. The folA and folP genes were sequenced and compared with reference sequences at NCBI. Only resistance to cotrimoxazole was significantly higher in the prophylaxis group (54.7% versus 15.5%, OR=6.59, 95% CI: 2.89–15.3, P<0.05). Resistance to amoxicillin, ceftriaxone, chloramphenicol, erythromycin, and tetracycline was 1.4%, 25.5%, 6.2%, 6.5%, and 29.6% of ...