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Transderm Scop

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Drug Uses

Transderm Scop is used to relieve nausea, vomiting, and dizziness associated with motion sickness. Transderm Scop is an anticholinergic medicine. Anticholinergics have many effects in the body. For example, they decrease the secretion of fluids, slow the stomach and intestine, and dilate the pupils.

How Taken

Transderm Scop comes as a patch to be placed on the skin behind your ear. Apply one patch to a clean, dry, hairless area behind the ear. The patch should be applied at least 4 hours before its effects will be needed. Each patch is good for 3 days. At the end of 3 days or when the Transderm Scop patch is no longer needed, remove the patch and throw it away. Wrap the patch in tissue or paper to avoid exposing anyone else to the remaining medication. Wash your hands and the area behind your ear thoroughly to remove any traces of Transderm Scop from the area. If a new patch needs to be applied, place a fresh patch on the hairless area behind your other ear.

Warnings/Precautions

Before using this medication, tell your doctor if you have kidney disease, liver disease, an enlarged prostate, difficulty urinating, bladder problems, or glaucoma. Transderm Scop is in the FDA pregnancy category C. This means that it is not known whether Transderm Scop will harm an unborn baby. Do not use Transderm Scop without first talking to your doctor if you are pregnant. It is not known whether Transderm Scop passes into breast milk. Do not use Transderm Scop without first talking to your doctor if you are breast-feeding a baby. Transderm Scop is not recommended for children use. Children are much more sensitive to the side effects of scopolamine.

Missed Dose

Remove the old patch as soon as you remember and apply a new patch to the same area behind the other ear. If it is almost time for the next dose, skip the missed dose altogether. Never take a double dose of Transderm Scop.

Possible Side Effects

Stop using Transderm Scop and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives). Other, less serious side effects may be more likely to occur. Continue to use Transderm Scop and talk to your doctor if you experience drowsiness; dry mouth, nose, or throat; restlessness, excitation, nervousness, or insomnia; blurred vision; dizziness; decreased appetite, nausea, or vomiting; difficulty urinating; or an irregular or fast heartbeat. Nausea, vomiting, dizziness, headache, and poor coordination have been reported when treatment lasting more than 3 days is discontinued. If you use Transderm Scop for more than 3 days, be aware that these side effects may occur when you stop. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Should be stored at controlled room temperature between 20°C - 25°C (68°F - 77°F).

Overdose

Seek emergency medical attention. Symptoms of a Transderm Scop overdose include drowsiness, dizziness, agitation, excitability, seizures or convulsions, hallucinations, and death.

More Information

Use caution when driving, operating machinery, or performing other hazardous activities. Transderm Scop may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are using Transderm Scop.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

Other info about Transderm-scop at Wikipedia.org and other resources:


DOMMINO: a database of macromolecular interactions
With the growing number of experimentally resolved structures of macromolecular complexes, it becomes clear that the interactions that involve protein structures are mediated not only by the protein domains, but also by various non-structured regions, such as interdomain linkers, or terminal sequences. Here, we present DOMMINO (http://dommino.org), a comprehensive database of macromolecular interactions that includes the interactions between protein domains, interdomain linkers, N- and C-terminal regions and protein peptides. The database complements SCOP domain annotations with domain predictions by SUPERFAMILY and is automatically updated every week. The database interface is designed to provide the user with a three-stage pipeline to study macromolecular interactions: (i) a flexible sea...

IndelFR: a database of indels in protein structures and their flanking regions
Insertion/deletion (indel) is one of the most common methods of protein sequence variation. Recent studies showed that indels could affect their flanking regions and they are important for protein function and evolution. Here, we describe the Indel Flanking Region Database (IndelFR, http://indel.bioinfo.sdu.edu.cn), which provides sequence and structure information about indels and their flanking regions in known protein domains. The indels were obtained through the pairwise alignment of homologous structures in SCOP superfamilies. The IndelFR database contains 2 925 017 indels with flanking regions extracted from 373 402 structural alignment pairs of 12 573 non-redundant domains from 1053 superfamilies. IndelFR provides access to information about indels and their flanking regions, includ...

PASS2 version 4: An update to the database of structure-based sequence alignments of structural domain superfamilies
Accurate structure-based sequence alignments of distantly related proteins are crucial in gaining insight about protein domains that belong to a superfamily. The PASS2 database provides alignments of proteins related at the superfamily level and are characterized by low sequence identity. We thus report an automated, updated version of the superfamily alignment database known as PASS2.4, consisting of 1961 superfamilies and 10 569 protein domains, which is in direct correspondence with SCOP (1.75) database. Database organization, improved methods for efficient structure-based sequence alignments and the analysis of extreme distantly related proteins within superfamilies formed the focus of this update. Alignment of family-specific functional residues can be realized using such alignments a...

Structural alphabet motif discovery and a structural motif database
This study proposes a general framework for structural motif discovery. The framework is based on a modular design in which the system components can be modified or replaced independently to increase its applicability to various studies. It is a two-stage approach that first converts protein 3D structures into structural alphabet sequences, and then applies a sequence motif-finding tool to these sequences to detect conserved motifs. We named the structural motif database we built the SA-Motifbase, which provides the structural information conserved at different hierarchical levels in SCOP. For each motif, SA-Motifbase presents its 3D view; alphabet letter preference; alphabet letter frequency distribution; and the significance. SA-Motifbase is available at http://bioinfo.cis.nctu.edu.tw/sa...

Does a shift in host plants trigger speciation in the Alpine leaf beetle Oreina speciosissima (Coleoptera, Chrysomelidae)?
Conclusions: The question of whether this case of ecological differentiation occurred in sympatry or allopatry remains open. Still, the observed pattern points towards ongoing divergence between the two ecotypes which is likely driven by a recent shift in host plant use. (Source: BMC Evolutionary Biology - Latest articles)


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